FC Cartagena

Cartagena was founded on 25 July 1995, in the place of Club Deportivo Balsicas, due to serious economic problems of the first team of the city, Cartagena FC, the first president Florentino Manzano was the founder. In the first eight years it was known as Cartagonova Fútbol Club, and first played in the third division in the 1998–99 season.

The club then changed its name to Fútbol Club Cartagena and Luis Oliver took over as president, starting his tenure with the club immerse in economic problems and close to relegation. Being saved from folding by local entrepreneur Francisco Gómez after the 2002–03 campaign, it consolidated itself in the third level and achieved another promotion, now to division two, in 2009.

Historic side Cartagena FC, which was founded much earlier, acted as reserve team between 2003 and 2009, eventually re-gaining its independence. In 2009–10's second division season Efesé nearly achieved another promotion, finishing eventually in fifth position; all promotion hopes were dashed in the 41st and penultimate matchday, with a 0–1 away loss against Recreativo de Huelva.

Cartagena was relegated from the second tier at the end of 2011–12. In May 2015, a late goal from Carlos Martínez saved the club from a further drop by winning a play-off on the away goals rule against Las Palmas Atlético. Three years later, the team fell at the final promotion hurdle to Extremadura UD by a single goal.

On 19 July 2020, Cartagena was promoted to Segunda Division after an 8-year absence.

On 13 April 2025, Cartagena was relegated to third division after five years stay in second division following a 1-2 defeated by Almería.