Head to Head
| NCAAF | 2022/11/19 18:00 | Mercer v Samford | W | 44-50 |
| NCAAF | 2021/10/02 22:00 | Samford v Mercer | L | 42-45 |
| NCAAF | 2021/04/17 17:00 | Mercer v Samford | W | 20-44 |
| NCAAF | 2019/11/02 23:00 | Samford v Mercer | L | 33-36 |
| NCAAF | 2018/09/15 19:00 | Mercer v Samford | L | 30-24 |
| NCAAF | 2017/11/04 19:00 | Mercer v Samford | W | 3-20 |
Home History
| NCAAF | 2022/12/10 00:00 | Samford v North Dakota State | L | 9-27 |
| NCAAF | 2022/12/03 20:00 | SE Louisiana v Samford | W | 42-48 |
| NCAAF | 2022/11/19 18:00 | Mercer v Samford | W | 44-50 |
| NCAAF | 2022/11/12 18:30 | Samford v Tennessee Chattanooga | W | 35-24 |
| NCAAF | 2022/11/05 19:00 | VMI v Samford | W | 15-34 |
| NCAAF | 2022/10/29 18:00 | Samford v The Citadel | W | 38-3 |
| NCAAF | 2022/10/22 19:30 | Samford v East Tennessee State | W | 55-45 |
| NCAAF | 2022/10/08 17:00 | Wofford v Samford | W | 14-28 |
Away History
| NCAAF | 2023/08/26 19:30 | North Alabama v Mercer | W | 7-17 |
| NCAAF | 2022/11/19 18:00 | Mercer v Samford | L | 44-50 |
| NCAAF | 2022/11/12 20:00 | Furman v Mercer | L | 23-13 |
| NCAAF | 2022/10/29 17:30 | Mercer v VMI | W | 55-14 |
| NCAAF | 2022/10/22 17:30 | Mercer v Tennessee Chattanooga | L | 21-41 |
| NCAAF | 2022/10/15 20:00 | East Tennessee State v Mercer | W | 33-55 |
| NCAAF | 2022/10/08 20:00 | Western Carolina v Mercer | W | 6-49 |
| NCAAF | 2022/10/01 17:30 | Mercer v Wofford | W | 42-7 |
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