Stadium: Rogers Place
Home Manager: Away Manager: Jay Woodcroft
| NHL | 2022/02/01 00:30 | EDM Oilers v OTT Senators | W | 2-3 |
| NHL | 2022/01/16 03:00 | OTT Senators v EDM Oilers | W | 6-4 |
| NHL | 2021/04/08 23:00 | EDM Oilers v OTT Senators | L | 3-1 |
| NHL | 2021/04/07 21:00 | EDM Oilers v OTT Senators | L | 4-2 |
| NHL | 2021/03/13 02:00 | OTT Senators v EDM Oilers | L | 2-6 |
| NHL | 2021/03/11 01:00 | OTT Senators v EDM Oilers | L | 1-7 |
| NHL | 2021/03/09 02:00 | OTT Senators v EDM Oilers | L | 2-3 |
| NHL | 2021/02/10 00:00 | EDM Oilers v OTT Senators | L | 3-2 |
| NHL | 2022/12/10 18:30 | OTT Senators v NSH Predators | W | 3-2 |
| NHL | 2022/12/09 01:30 | OTT Senators v DAL Stars | L | 3-4 |
| NHL | 2022/12/07 00:00 | LA Kings v OTT Senators | L | 5-2 |
| NHL | 2022/12/04 00:00 | SJ Sharks v OTT Senators | W | 2-5 |
| NHL | 2022/12/03 00:00 | OTT Senators v NY Rangers | W | 3-2 |
| NHL | 2022/12/01 00:00 | NY Rangers v OTT Senators | L | 3-1 |
| NHL | 2022/11/28 03:30 | OTT Senators v LA Kings | W | 3-2 |
| NHL | 2022/11/25 20:00 | OTT Senators v ANA Ducks | W | 5-1 |
| NHL | 2022/12/10 02:00 | MIN Wild v EDM Oilers | W | 2-5 |
| NHL | 2022/12/08 02:30 | ARZ Coyotes v EDM Oilers | W | 2-8 |
| NHL | 2022/12/06 01:30 | WAS Capitals v EDM Oilers | L | 3-2 |
| NHL | 2022/12/04 00:00 | MTL Canadiens v EDM Oilers | W | 3-5 |
| NHL | 2022/12/02 01:00 | EDM Oilers v MIN Wild | L | 3-5 |
| NHL | 2022/12/01 02:30 | EDM Oilers v CHI Blackhawks | W | 5-4 |
| NHL | 2022/11/29 02:30 | FLA Panthers v EDM Oilers | W | 3-4 |
| NHL | 2022/11/26 18:00 | EDM Oilers v NY Rangers | W | 4-3 |