Stadium: Bon Secours Wellness Arena Round: 124
Home Manager: Mike Krzyzewski Away Manager: Tom Izzo
| NCAAB | 2020/12/02 00:30 | Michigan State v Duke | W | 75-69 |
| NCAAB | 2019/12/04 02:30 | Duke v Michigan State | L | 87-75 |
| NCAAB | 2019/03/31 21:05 | Michigan State v Duke | W | 68-67 |
| NCAAB | 2017/11/15 00:00 | Michigan State v Duke | L | 81-88 |
| NCAAB | 2016/11/30 02:30 | Michigan State v Duke | L | 69-78 |
| NCAAB | 2015/04/04 22:09 | Duke v Michigan State | L | 81-61 |
| NCAAB | 2014/11/19 00:00 | Duke v Michigan State | L | 81-71 |
| NCAAB | 2011/11/15 12:00 | Duke v Michigan State | L | 74-69 |
| NCAAB | 2022/03/06 21:30 | Maryland v Michigan State | W | 67-77 |
| NCAAB | 2022/03/04 00:00 | Michigan State v Ohio State | L | 69-80 |
| NCAAB | 2022/03/02 01:30 | Michigan State v Michigan | L | 70-87 |
| NCAAB | 2022/02/26 17:00 | Purdue v Michigan State | W | 65-68 |
| NCAAB | 2022/02/23 00:00 | Michigan State v Iowa | L | 60-86 |
| NCAAB | 2022/02/19 17:00 | Illinois v Michigan State | L | 79-74 |
| NCAAB | 2022/02/16 00:00 | Michigan State v Penn State | L | 58-62 |
| NCAAB | 2022/02/12 20:30 | Indiana v Michigan State | W | 61-76 |
| NCAAB | 2022/03/05 23:00 | North Carolina v Duke | L | 94-81 |
| NCAAB | 2022/03/02 01:00 | Duke v Pittsburgh | W | 86-56 |
| NCAAB | 2022/02/26 23:00 | Duke v Syracuse | W | 97-72 |
| NCAAB | 2022/02/24 00:00 | Duke v Virginia | W | 65-61 |
| NCAAB | 2022/02/19 23:00 | Florida State v Duke | W | 70-88 |
| NCAAB | 2022/02/16 00:00 | Wake Forest v Duke | W | 74-76 |
| NCAAB | 2022/02/12 22:00 | Duke v Boston College | W | 72-61 |
| NCAAB | 2022/02/11 01:00 | Duke v Clemson | W | 82-64 |