Stadium: G.B. Hodge Center
Home Manager: Dave Dickerson Away Manager: Ryan Saunders
| NCAAB | 2021/02/27 21:00 | USC Upstate v High Point | L | 60-65 |
| NCAAB | 2021/02/22 23:00 | Gardner Webb v USC Upstate | L | 69-58 |
| NCAAB | 2021/02/18 22:00 | USC Upstate v Presbyterian | W | 65-51 |
| NCAAB | 2021/02/15 23:00 | USC Upstate v Presbyterian | L | 65-75 |
| NCAAB | 2021/02/13 00:00 | USC Upstate v Campbell | L | 49-64 |
| NCAAB | 2021/02/12 00:00 | USC Upstate v Campbell | L | 71-72 |
| NCAAB | 2021/02/08 22:00 | Gardner Webb v USC Upstate | W | 69-77 |
| NCAAB | 2021/02/05 23:00 | USC Upstate v Radford | L | 66-102 |