Stadium: Jenny Craig Pavilion
Home Manager: Sam Scholl Away Manager: Herb Sendek
| NCAAB | 2021/02/19 02:00 | San Diego v Santa Clara | L | 71-60 |
| NCAAB | 2021/01/17 22:00 | Santa Clara v San Diego | W | 69-63 |
| NCAAB | 2020/01/25 23:00 | Santa Clara v San Diego | W | 65-52 |
| NCAAB | 2020/01/04 22:00 | San Diego v Santa Clara | W | 63-80 |
| NCAAB | 2019/03/09 04:20 | San Diego v Santa Clara | L | 62-45 |
| NCAAB | 2019/01/04 03:00 | San Diego v Santa Clara | W | 56-68 |
| NCAAB | 2018/02/10 21:00 | San Diego v Santa Clara | W | 64-70 |
| NCAAB | 2018/01/26 03:00 | Santa Clara v San Diego | L | 58-66 |
| NCAAB | 2021/12/15 02:00 | Santa Clara v Boise State | L | 60-72 |
| NCAAB | 2021/12/12 02:00 | Santa Clara v California | L | 60-72 |
| NCAAB | 2021/12/08 02:00 | Mount St Marys v Santa Clara | W | 77-88 |
| NCAAB | 2021/12/04 22:00 | Louisiana Tech v Santa Clara | L | 78-75 |
| NCAAB | 2021/12/01 02:00 | Hawaii v Santa Clara | W | 58-70 |
| NCAAB | 2021/11/28 00:30 | UC Irvine v Santa Clara | L | 69-64 |
| NCAAB | 2021/11/25 06:00 | Fresno St v Santa Clara | L | 59-52 |
| NCAAB | 2021/11/23 03:30 | TCU v Santa Clara | W | 66-85 |
| NCAAB | 2021/12/12 03:00 | San Diego v Cal Lutheran | W | 84-55 |
| NCAAB | 2021/12/05 21:00 | Cal Poly SLO v San Diego | W | 51-52 |
| NCAAB | 2021/12/02 03:00 | San Diego v Fresno St | L | 43-63 |
| NCAAB | 2021/11/28 23:00 | CS Northridge v San Diego | L | 56-52 |
| NCAAB | 2021/11/26 20:30 | Illinois-Chicago v San Diego | W | 52-64 |
| NCAAB | 2021/11/25 18:30 | South Alabama v San Diego | L | 68-67 |
| NCAAB | 2021/11/20 03:00 | CS Fullerton v San Diego | L | 57-55 |
| NCAAB | 2021/11/18 03:30 | Cal Riverside v San Diego | W | 62-74 |