Stadium: Welsh-Ryan Arena
Home Manager: Tom Izzo Away Manager: Chris Collins
| NCAAB | 2020/12/21 00:00 | Michigan State v Northwestern | L | 65-79 |
| NCAAB | 2020/01/29 23:30 | Northwestern v Michigan State | W | 50-79 |
| NCAAB | 2019/12/19 01:00 | Michigan State v Northwestern | W | 77-72 |
| NCAAB | 2019/01/03 01:30 | Northwestern v Michigan State | W | 55-81 |
| NCAAB | 2018/02/17 19:00 | Michigan State v Northwestern | W | 65-60 |
| NCAAB | 2016/12/30 23:00 | Northwestern v Michigan State | W | 52-61 |
| NCAAB | 2016/01/29 02:00 | Northwestern v Michigan State | W | 45-76 |
| NCAAB | 2015/02/11 00:00 | Northwestern v Michigan State | W | 44-68 |
| NCAAB | 2021/03/19 02:19 | UCLA v Michigan State | L | 86-80 |
| NCAAB | 2021/03/11 16:30 | Michigan State v Maryland | L | 57-68 |
| NCAAB | 2021/03/07 21:30 | Michigan v Michigan State | W | 64-70 |
| NCAAB | 2021/03/05 00:00 | Michigan State v Michigan | L | 50-69 |
| NCAAB | 2021/03/03 01:00 | Indiana v Michigan State | W | 58-64 |
| NCAAB | 2021/02/28 19:00 | Michigan State v Maryland | L | 55-73 |
| NCAAB | 2021/02/26 02:00 | Ohio State v Michigan State | W | 67-71 |
| NCAAB | 2021/02/24 00:00 | Illinois v Michigan State | W | 72-81 |
| NCAAB | 2021/03/10 23:30 | Minnesota v Northwestern | L | 51-46 |
| NCAAB | 2021/03/07 18:30 | Nebraska v Northwestern | W | 78-79 |
| NCAAB | 2021/03/04 02:00 | Maryland v Northwestern | W | 55-60 |
| NCAAB | 2021/02/26 02:00 | Northwestern v Minnesota | W | 67-59 |
| NCAAB | 2021/02/22 00:00 | Wisconsin v Northwestern | L | 68-51 |
| NCAAB | 2021/02/17 02:00 | Northwestern v Illinois | L | 66-73 |
| NCAAB | 2021/02/13 22:00 | Northwestern v Rutgers | L | 50-64 |
| NCAAB | 2021/02/10 22:30 | Indiana v Northwestern | L | 79-76 |