Stadium: Raiford G. Trask Coliseum
Home Manager: Robin Harmony Away Manager: Tina Martin
| WNCAAB | 2021/03/10 19:30 | UNC Wilmington (W) v Coll of Charleston (W) | L | 60-47 |
| WNCAAB | 2021/02/28 18:00 | Coll of Charleston (W) v UNC Wilmington (W) | L | 54-61 |
| WNCAAB | 2021/02/27 00:00 | Coll of Charleston (W) v UNC Wilmington (W) | L | 66-68 |
| WNCAAB | 2020/03/11 18:00 | Coll of Charleston (W) v UNC Wilmington (W) | L | 55-69 |
| WNCAAB | 2020/02/23 19:00 | UNC Wilmington (W) v Coll of Charleston (W) | L | 74-50 |
| WNCAAB | 2020/01/26 18:00 | Coll of Charleston (W) v UNC Wilmington (W) | W | 67-63 |
| WNCAAB | 2019/03/08 23:30 | Coll of Charleston (W) v UNC Wilmington (W) | L | 62-66 |
| WNCAAB | 2019/01/04 16:30 | UNC Wilmington (W) v Coll of Charleston (W) | L | 71-49 |
| WNCAAB | 2021/12/19 19:00 | Florida A&M (W) v Coll of Charleston (W) | W | 60-83 |
| WNCAAB | 2021/12/18 21:30 | Coll of Charleston (W) v Radford (W) | W | 77-59 |
| WNCAAB | 2021/12/16 00:00 | Coll of Charleston (W) v Agnes Scott Women | W | 102-25 |
| WNCAAB | 2021/12/08 00:00 | Coll of Charleston (W) v UNC Greensboro (W) | W | 75-68 |
| WNCAAB | 2021/12/02 22:30 | Coll of Charleston (W) v Charleston Southern (W) | W | 96-60 |
| WNCAAB | 2021/11/30 22:00 | Georgia Southern (W) v Coll of Charleston (W) | L | 85-65 |
| WNCAAB | 2021/11/27 19:00 | North Florida (W) v Coll of Charleston (W) | L | 86-76 |
| WNCAAB | 2021/11/24 00:00 | Tarleton State (W) v Coll of Charleston (W) | L | 69-59 |
| WNCAAB | 2021/12/22 19:00 | UNC Wilmington (W) v UNC Greensboro (W) | W | 45-42 |
| WNCAAB | 2021/12/19 19:00 | East Carolina (W) v UNC Wilmington (W) | L | 79-50 |
| WNCAAB | 2021/12/16 23:00 | UNC Wilmington (W) v Norfolk State (W) | L | 56-67 |
| WNCAAB | 2021/12/01 22:00 | UNC Wilmington (W) v Winthrop (W) | W | 55-48 |
| WNCAAB | 2021/11/27 19:00 | Radford (W) v UNC Wilmington (W) | L | 51-50 |
| WNCAAB | 2021/11/23 19:00 | UNC Wilmington (W) v Campbell (W) | L | 42-53 |
| WNCAAB | 2021/11/20 19:00 | Coastal Carolina (W) v UNC Wilmington (W) | L | 73-62 |
| WNCAAB | 2021/11/18 23:00 | UNC Wilmington (W) v Maryland (W) | L | 66-108 |