Stadium: KeyBank Center Round: 1
Home Manager: Claude Julien Away Manager: Phil Housley
| NHL | 2017/04/05 23:30 | MTL Canadiens v BUF Sabres | L | 1-2 |
| NHL | 2017/02/01 00:30 | BUF Sabres v MTL Canadiens | W | 2-5 |
| NHL | 2017/01/22 00:00 | BUF Sabres v MTL Canadiens | L | 3-2 |
| NHL | 2016/10/13 23:00 | MTL Canadiens v BUF Sabres | W | 4-1 |
| NHL | 2017/04/23 00:00 | MTL Canadiens v NY Rangers | L | 1-3 |
| NHL | 2017/04/20 23:00 | NY Rangers v MTL Canadiens | L | 3-2 |
| NHL | 2017/04/18 23:00 | MTL Canadiens v NY Rangers | L | 1-2 |
| NHL | 2017/04/16 23:00 | MTL Canadiens v NY Rangers | W | 3-1 |
| NHL | 2017/04/14 23:00 | NY Rangers v MTL Canadiens | W | 3-4 |
| NHL | 2017/04/12 23:00 | NY Rangers v MTL Canadiens | L | 2-0 |
| NHL | 2017/04/08 23:00 | MTL Canadiens v DET Red Wings | W | 3-2 |
| NHL | 2017/04/07 23:30 | TB Lightning v MTL Canadiens | L | 4-2 |
| NHL | 2017/04/09 21:00 | BUF Sabres v TB Lightning | L | 2-4 |
| NHL | 2017/04/08 23:00 | BUF Sabres v FLA Panthers | L | 0-3 |
| NHL | 2017/04/05 23:30 | MTL Canadiens v BUF Sabres | W | 1-2 |
| NHL | 2017/04/03 23:00 | TOR Maple Leafs v BUF Sabres | L | 4-2 |
| NHL | 2017/04/02 19:00 | NY Islanders v BUF Sabres | L | 4-2 |
| NHL | 2017/03/28 23:00 | BUF Sabres v CLB Blue Jackets | L | 1-3 |
| NHL | 2017/03/27 23:00 | FLA Panthers v BUF Sabres | W | 2-4 |
| NHL | 2017/03/25 23:00 | TOR Maple Leafs v BUF Sabres | W | 2-5 |