[2] NE Patriots 17-27 IND Colts [10] 2021-10-17 03:15
Stadium: Lucas Oil Stadium Round: 1
Home Manager: Frank Reich Away Manager: Bill Belichick
Head to Head
| NFL | 2018/10/05 00:20 | IND Colts v NE Patriots | W | 24-38 |
| NFL | 2015/10/19 00:30 | IND Colts v NE Patriots | W | 27-34 |
| NFL | 2015/01/18 23:40 | NE Patriots v IND Colts | W | 45-7 |
| NFL | 2014/11/17 01:30 | IND Colts v NE Patriots | W | 20-42 |
Home History
| NFL | 2021/10/10 17:00 | NE Patriots v HOU Texans | W | 25-22 |
| NFL | 2021/10/04 00:20 | TB Buccaneers v NE Patriots | L | 19-17 |
| NFL | 2021/09/26 17:00 | NO Saints v NE Patriots | L | 28-13 |
| NFL | 2021/09/19 17:00 | NE Patriots v NY Jets | W | 25-6 |
| NFL | 2021/09/12 20:25 | MIA Dolphins v NE Patriots | L | 17-16 |
| NFL Preseason | 2021/08/29 22:00 | NE Patriots v NY Giants | W | 22-20 |
| NFL Preseason | 2021/08/19 23:30 | NE Patriots v PHI Eagles | W | 35-0 |
| NFL Preseason | 2021/08/12 23:30 | WAS Commanders v NE Patriots | W | 13-22 |
Away History
| NFL | 2021/10/12 00:15 | IND Colts v BAL Ravens | L | 25-31 |
| NFL | 2021/10/03 17:00 | IND Colts v MIA Dolphins | W | 27-17 |
| NFL | 2021/09/26 17:00 | IND Colts v TEN Titans | L | 16-25 |
| NFL | 2021/09/19 17:00 | LA Rams v IND Colts | L | 27-24 |
| NFL | 2021/09/12 17:00 | SEA Seahawks v IND Colts | L | 28-16 |
| NFL Preseason | 2021/08/27 23:00 | IND Colts v DET Lions | W | 27-17 |
| NFL Preseason | 2021/08/22 00:00 | IND Colts v MIN Vikings | W | 12-10 |
| NFL Preseason | 2021/08/15 17:00 | CAR Panthers v IND Colts | W | 18-21 |
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