Stadium: Memorial Stadium/Bob Cunningham Field Round: 1
| NCAAF | 2018/11/10 19:00 | Sioux Falls Cougars v Wayne State Wildcats | L | 26-7 |
| NCAAF | 2018/11/03 17:05 | Upper Iowa v Wayne State Wildcats | W | 35-42 |
| NCAAF | 2018/10/27 18:00 | Wayne State Wildcats v Minnesota State Mankato Mavericks | L | 2-55 |
| NCAAF | 2018/10/20 18:00 | Minot State Beavers v Wayne State Wildcats | W | 0-34 |
| NCAAF | 2018/10/13 18:00 | Wayne State Wildcats v Minnesota State University Moorhead Dragons | L | 22-28 |
| NCAAF | 2018/10/06 18:00 | St Cloud State Huskies v Wayne State Wildcats | L | 23-17 |
| NCAAF | 2018/09/29 18:00 | Wayne State Wildcats v Bemidji State Beavers | L | 10-27 |
| NCAAF | 2018/09/20 23:00 | Concordia University Golden Bears v Wayne State Wildcats | L | 29-7 |
| NCAAF | 2018/11/10 19:00 | Minnesota Duluth Bulldogs v Northern State Wolves | L | 40-13 |
| NCAAF | 2018/11/03 18:00 | Northern State Wolves v Minnesota Crookston Golden Eagles | W | 27-0 |
| NCAAF | 2018/10/27 19:00 | University of Mary Marauders v Northern State Wolves | W | 23-28 |
| NCAAF | 2018/10/20 22:00 | Southwest Minnesota State Mustangs v Northern State Wolves | L | 35-7 |
| NCAAF | 2018/10/13 18:00 | Northern State Wolves v Augustana Vikings | L | 21-42 |
| NCAAF | 2018/10/06 17:00 | Concordia University Golden Bears v Northern State Wolves | W | 28-35 |
| NCAAF | 2018/09/29 19:30 | Northern State Wolves v Winona State Warriors | L | 15-22 |
| NCAAF | 2018/09/22 18:00 | Northern State Wolves v St Cloud State Huskies | L | 14-19 |