| Player | Team | Status | Date |
|---|---|---|---|
| Ulises Segura |
Deportivo Saprissa
|
Injured | 04/24 00:00 |
| Alec Kann |
FC Cincinnati
|
Injured | 07/20 00:00 |
| Isaiah Foster |
FC Cincinnati
|
Injured | 08/24 00:00 |
| Matt Miazga |
FC Cincinnati
|
Injured | 08/24 00:00 |
| Leo Afonso |
Inter Miami CF
|
Injured | 11/09 00:00 |
| Dany Rosero |
Sporting Kansas City
|
Injured | 10/05 00:00 |
| Jacob Davis |
Sporting Kansas City
|
Injured | 10/19 00:00 |
| Khiry Shelton |
Sporting Kansas City
|
Injured | 10/19 00:00 |
| Jeevan Badwal |
Vancouver Whitecaps
|
Injured | 10/19 00:00 |
| Malte Amundsen |
Columbus Crew
|
Injured | 10/29 00:00 |
| Ian Fray |
Inter Miami CF
|
Injured | 11/02 00:00 |
| David Ruiz |
Inter Miami CF
|
Injured | 11/09 00:00 |
| Danny Musovski |
Seattle Sounders
|
Injured | 11/03 00:00 |
| Lorenzo Dellavalle |
Los Angeles FC
|
Injured | 11/03 00:00 |
| Yannick Bright |
Inter Miami CF
|
Injured | 11/09 00:00 |
| Paul Rothrock |
Seattle Sounders
|
Injured | 11/30 00:00 |
| Reed Baker-Whiting |
Seattle Sounders
|
Doubtful | 11/30 00:00 |
| Yeimar Gomez Andrade |
Seattle Sounders
|
Doubtful | 11/30 00:00 |
| Riqui Puig |
LA Galaxy
|
Injured | 12/07 00:00 |
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