The 2021–22 FA Women's National League was the 30th season of the competition, and the fourth since a restructure and rebranding of the top four tiers of English football by The Football Association. Starting in 1991, it was previously known as the FA Women's Premier League. It sits at the third and fourth levels of the women's football pyramid, below the FA Women's Championship and above the eight regional football leagues.
The league featured six regional divisions: the Northern and Southern Premier divisions at level three of the pyramid, and Division One North, Division One Midlands, Division One South East, and Division One South West at the fourth level. The league consisted of 76 teams, divided into six divisions of 13 teams apart from the Southern Premier Division which contains 14 teams, Division One North which contains 12 teams, and Division One South West which contains 11 teams. At the end of the season the winners of the Northern and Southern Premier divisions qualified for a play-off match to decide the overall National League champion. Southampton F.C. beat Wolverhampton Wanderers in the final and were promoted to the FA Women's Championship.