| NCAAF | 11/22 17:00 | 122 | Framingham State Rams v Lagrange Panthers | W | 21-24 | |
| NCAAF | 11/15 18:00 | 1 | Southern Virginia Knights v Lagrange Panthers | W | 27-65 | |
| NCAAF | 11/08 18:00 | 1 | Lagrange Panthers v Belhaven Blazers | W | 38-6 | |
| NCAAF | 11/01 16:00 | 1 | Greensboro v Lagrange Panthers | W | 20-49 | |
| NCAAF | 10/25 17:00 | 1 | Lagrange Panthers v Huntingdon Hawks | W | 30-14 | |
| NCAAF | 10/18 17:00 | 1 | Lagrange Panthers v Brevard Tornados | W | 17-10 | |
| NCAAF | 10/11 17:00 | 1 | Methodist Monarchs v Lagrange Panthers | W | 7-26 | |
| NCAAF | 10/04 17:00 | 1 | Lagrange Panthers v Nc Wesleyan Battling Bishops | W | 41-24 | |
| NCAAF | 09/20 17:00 | 1 | Lagrange Panthers v Centre Colonels | W | 20-6 | |
| NCAAF | 09/13 23:30 | 1 | Lagrange Panthers v Berry Vikings | L | 0-48 | |
| NCAAF | 09/07 00:00 | 1 | Point University Skyhawks v Lagrange Panthers | W | 14-36 | |
| NCAAF | 11/16 18:00 | 1 | Lagrange Panthers v Southern Virginia Knights | W | 50-24 | |
| NCAAF | 11/09 18:00 | 1 | Belhaven Blazers v Lagrange Panthers | L | 36-9 | |
| NCAAF | 11/02 18:00 | 1 | Huntingdon Hawks v Lagrange Panthers | W | 21-24 | |
| NCAAF | 10/26 17:00 | 1 | Lagrange Panthers v Greensboro | W | 52-16 | |
| NCAAF | 10/19 19:30 | 1 | Brevard Tornados v Lagrange Panthers | W | 21-26 | |
| NCAAF | 10/12 16:00 | 1 | Nc Wesleyan Battling Bishops v Lagrange Panthers | W | 9-31 | |
| NCAAF | 10/05 17:00 | 1 | Lagrange Panthers v Maryville Scots | L | 13-38 | |
| NCAAF | 09/28 17:00 | 1 | Lagrange Panthers v Methodist Monarchs | W | 40-24 | |
| NCAAF | 09/14 22:00 | - |
PAOK
v
Lagrange Panthers |
L | 44-14 | |
| NCAAF | 09/07 00:00 | 1 | East Texas Baptist Tigers v Lagrange Panthers | L | 57-12 | |
| NCAAF | 11/04 17:00 | 1 | Methodist Monarchs v Lagrange Panthers | L | 38-27 | |
| NCAAF | 10/28 19:00 | 1 | Lagrange Panthers v Brevard Tornados | L | 20-30 | |
| NCAAF | 10/21 17:00 | 1 | Maryville Scots v Lagrange Panthers | L | 26-6 | |
| NCAAF | 10/14 17:00 | 1 | Lagrange Panthers v Belhaven Blazers | L | 20-42 | |
| NCAAF | 10/07 17:00 | 1 | Lagrange Panthers v Nc Wesleyan Battling Bishops | L | 14-35 | |
| NCAAF | 09/30 17:00 | 1 | Southern Virginia Knights v Lagrange Panthers | L | 52-26 | |
| NCAAF | 09/23 17:00 | 1 | Lagrange Panthers v Huntingdon Hawks | L | 6-41 | |
| NCAAF | 09/16 16:00 | 1 | Ferrum Panthers v Lagrange Panthers | L | 13-10 | |
| NCAAF | 09/09 22:00 | 1 | Lagrange Panthers v Berry Vikings | L | 3-70 |