Stadium: Winthrop Coliseum
Home Manager: Jason Williams Away Manager: Semeka Randall Lay
| WNCAAB | 2022/02/09 23:00 | Winthrop (W) v USC Upstate (W) | W | 47-59 |
| WNCAAB | 2022/02/09 00:00 | USC Upstate (W) v Winthrop (W) | W | 73-43 |
| WNCAAB | 2020/12/18 23:00 | Winthrop (W) v USC Upstate (W) | W | 49-56 |
| WNCAAB | 2020/12/17 23:00 | USC Upstate (W) v Winthrop (W) | L | 54-59 |
| WNCAAB | 2020/03/10 23:00 | Winthrop (W) v USC Upstate (W) | W | 57-60 |
| WNCAAB | 2020/03/07 19:00 | USC Upstate (W) v Winthrop (W) | W | 66-59 |
| WNCAAB | 2020/01/09 23:00 | USC Upstate (W) v Winthrop (W) | L | 38-52 |
| WNCAAB | 2019/02/26 23:00 | Winthrop (W) v USC Upstate (W) | W | 49-58 |
| WNCAAB | 2019/01/11 00:00 | USC Upstate (W) v Winthrop (W) | W | 76-50 |