Stadium: Kalamaria Stadium Round: 34
Home Manager: Dimitris Kalaitzidis Away Manager: Juan Ramon Rocha
| Greece Super League 2 | 2022/02/06 12:45 | Thesprotos v Apollon Pontou FC | W | 1-2 |
| Greece Football League | 2021/05/26 14:00 | Thesprotos v Apollon Pontou FC | W | 1-2 |
| Greece Football League | 2021/03/28 12:00 | Apollon Pontou FC v Thesprotos | L | 0-1 |
| Greece Super League 2 | 2022/02/06 12:45 | Thesprotos v Apollon Pontou FC | W | 1-2 |
| Greece Super League 2 | 2022/01/30 12:45 | Apollon Pontou FC v Xanthi | D | 0-0 |
| Greece Super League 2 | 2022/01/26 13:00 | Veria v Apollon Pontou FC | L | 5-0 |
| Greece Super League 2 | 2022/01/23 12:45 | Pierikos v Apollon Pontou FC | L | 1-0 |
| Greece Super League 2 | 2022/01/19 13:00 | Apollon Pontou FC v Iraklis 1908 FC | D | 1-1 |
| Greece Super League 2 | 2021/12/29 13:00 | Panserraikos v Apollon Pontou FC | W | 2-4 |
| Greece Super League 2 | 2021/12/22 13:00 | Apollon Pontou FC v Kavala | W | 7-0 |
| Greece Super League 2 | 2021/12/18 12:45 | Apollon Pontou FC v Olympiacos B | D | 0-0 |
| Greece Super League 2 | 2022/02/06 12:45 | Thesprotos v Apollon Pontou FC | L | 1-2 |
| Greece Super League 2 | 2022/02/02 13:00 | Apollon Larissa v Thesprotos | L | 2-1 |
| Greece Super League 2 | 2022/01/30 12:45 | Veria v Thesprotos | L | 2-1 |
| Greece Super League 2 | 2022/01/23 12:45 | Thesprotos v Iraklis 1908 FC | L | 1-5 |
| Greece Super League 2 | 2022/01/19 13:00 | Thesprotos v Larissa | D | 0-0 |
| Greece Super League 2 | 2022/01/16 12:45 | Panserraikos v Thesprotos | D | 2-2 |
| Greece Super League 2 | 2022/01/12 13:00 | Thesprotos v Olympiacos B | W | 2-1 |
| Greece Super League 2 | 2021/12/29 13:00 | Trikala v Thesprotos | L | 2-1 |