Stadium: VEB Arena Round: 16
Referee: Sergey Gennadyevich Karasev Home Manager: Aleksey Vladimirovich Berezutski Away Manager: Sergey Semak
| Russia Premier League | 2021/03/17 17:00 | CSKA Moscow v Zenit St Petersburg | L | 2-3 |
| Russia Premier League | 2020/08/19 17:00 | Zenit St Petersburg v CSKA Moscow | L | 2-1 |
| Russia Premier League | 2020/06/20 16:00 | CSKA Moscow v Zenit St Petersburg | L | 0-4 |
| Europe Friendlies | 2020/02/09 12:00 | Zenit St Petersburg v CSKA Moscow | L | 3-2 |
| Russia Premier League | 2019/11/02 16:00 | Zenit St Petersburg v CSKA Moscow | D | 1-1 |
| Russia Premier League | 2019/05/12 16:00 | Zenit St Petersburg v CSKA Moscow | L | 3-1 |
| Russia Premier League | 2018/11/11 16:00 | CSKA Moscow v Zenit St Petersburg | W | 2-0 |
| Russia Premier League | 2018/04/29 13:30 | Zenit St Petersburg v CSKA Moscow | D | 0-0 |
| Russia Premier League | 2021/07/31 17:00 | CSKA Moscow v Lokomotiv Moscow | L | 1-2 |
| Russia Premier League | 2021/07/25 17:00 | CSKA Moscow v FC Ufa | W | 1-0 |
| Europe Friendlies | 2021/07/19 14:00 | CSKA Moscow v FC Nizhny Novgorod | W | 2-1 |
| Europe Friendlies | 2021/07/13 16:00 | FC Vion Zlate Moravce v CSKA Moscow | W | 0-2 |
| Europe Friendlies | 2021/07/09 15:00 | Admira Wacker v CSKA Moscow | W | 0-1 |
| Europe Friendlies | 2021/07/05 16:00 | CSKA Moscow v FC Copenhagen | L | 0-1 |
| Europe Friendlies | 2021/06/27 16:00 | SV Kapfenberg v CSKA Moscow | W | 0-1 |
| Europe Friendlies | 2021/06/23 16:00 | Wiener Neustadt v CSKA Moscow | W | 1-3 |
| Russia Premier League | 2021/08/01 17:00 | Rostov v Zenit St Petersburg | W | 2-4 |
| Russia Premier League | 2021/07/24 14:30 | FK Khimki v Zenit St Petersburg | W | 1-3 |
| Russia Super Cup | 2021/07/17 16:00 | Zenit St Petersburg v Lokomotiv Moscow | W | 3-0 |
| Europe Friendlies | 2021/07/11 14:30 | Karlsruher SC v Zenit St Petersburg | W | 1-3 |
| Europe Friendlies | 2021/07/07 16:00 | Zenit St Petersburg v Werder Bremen | D | 2-2 |
| Europe Friendlies | 2021/07/03 14:00 | Schalke v Zenit St Petersburg | D | 0-0 |
| Russia Premier League | 2021/05/16 11:00 | FK Tambov v Zenit St Petersburg | W | 1-5 |
| Russia Premier League | 2021/05/08 11:00 | FC Ufa v Zenit St Petersburg | D | 0-0 |