Head to Head
| Mexico Liga MX Femenil | 2025/04/15 01:00 | Leon (W) v Santos Laguna (W) | W | 3-1 |
| Mexico Liga MX Femenil | 2024/10/18 23:00 | Santos Laguna (W) v Leon (W) | L | 5-0 |
| Mexico Liga MX Femenil | 2024/04/30 01:05 | Leon (W) v Santos Laguna (W) | W | 4-0 |
| Mexico Liga MX Femenil | 2023/10/21 03:10 | Santos Laguna (W) v Leon (W) | D | 2-2 |
| Mexico Liga MX Femenil | 2023/04/25 01:06 | Leon (W) v Santos Laguna (W) | D | 1-1 |
| Mexico Liga MX Femenil | 2022/08/02 00:00 | Santos Laguna (W) v Leon (W) | W | 1-2 |
| Mexico Liga MX Femenil | 2022/02/08 01:00 | Santos Laguna (W) v Leon (W) | W | 1-3 |
| Mexico Liga MX Femenil | 2021/08/24 00:00 | Leon (W) v Santos Laguna (W) | L | 1-6 |
Home History
| Mexico Liga MX Femenil | 2025/04/19 02:10 | Monterrey (W) v Leon (W) | L | 2-0 |
| Mexico Liga MX Femenil | 2025/04/15 01:00 | Leon (W) v Santos Laguna (W) | W | 3-1 |
| Mexico Liga MX Femenil | 2025/03/29 23:00 | Leon (W) v Unam Pumas (W) | L | 2-3 |
| Mexico Liga MX Femenil | 2025/03/22 21:45 | Cruz Azul (W) v Leon (W) | W | 1-2 |
| Mexico Liga MX Femenil | 2025/03/18 01:00 | Leon (W) v Chivas Guadalajara (W) | L | 1-3 |
| Mexico Liga MX Femenil | 2025/03/14 00:00 | Necaxa (W) v Leon (W) | L | 1-0 |
| Mexico Liga MX Femenil | 2025/03/11 01:00 | Leon (W) v Queretaro (W) | D | 0-0 |
| Mexico Liga MX Femenil | 2025/03/03 00:00 | Tijuana (W) v Leon (W) | W | 2-3 |
Away History
| Mexico Liga MX Femenil | 2025/04/18 03:05 | Mazatlan FC (W) v Santos Laguna (W) | W | 1-2 |
| Mexico Liga MX Femenil | 2025/04/15 01:00 | Leon (W) v Santos Laguna (W) | L | 3-1 |
| Mexico Liga MX Femenil | 2025/03/29 02:00 | Santos Laguna (W) v Club America (W) | L | 0-3 |
| Mexico Liga MX Femenil | 2025/03/23 18:00 | Puebla (W) v Santos Laguna (W) | L | 2-1 |
| Mexico Liga MX Femenil | 2025/03/19 03:00 | Santos Laguna (W) v Monterrey (W) | L | 1-3 |
| Mexico Liga MX Femenil | 2025/03/15 03:06 | Tigres UANL (W) v Santos Laguna (W) | L | 5-0 |
| Mexico Liga MX Femenil | 2025/03/11 01:00 | Santos Laguna (W) v Cruz Azul (W) | L | 0-1 |
| Mexico Liga MX Femenil | 2025/03/05 01:00 | Queretaro (W) v Santos Laguna (W) | L | 3-0 |
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